Get 404 page not found when browsing a web service you know is there.
For example, from IIS you right-click and select “Browse” on the .svc file (so you know it is really there). NOTE: the 404 is a “red herring” an outright lie – a bad error given to us by Microsoft to confuse us.

Bug Scenario: You are using C# variable in Mapping Functoids.
You run a map through “Test Map” and it works fine each time.
You run a file through a receive location, running the same map. Works great first time, but second time it maps nothing (or behaves differently). When you restart BizTalk Host Instance, it works fine first time, but not second time.
Why are we using a variable in the first place? The ideas was to map a field just one time (in a loop). So once the field is mapped, we need to set a flag not to map it again.

The Messaging Engine failed to register the adapter for “SOAP”
for the receive location
“/TMAC.Adfitech.BizTalk.Orchestrations_Proxy/ImagingInterfaceLoanDataPull.asmx”.

Please verify that the receive location exists,
and that the isolated adapter runs under an account that has access to the BizTalk databases.